A PDF is a digital representation of the print book, so while it can be loaded into most e-reader programs, it doesn't allow for resizable text or advanced, interactive functionality. A variety of techniques are available to select and introduce desirable traits4 in animals, plants, and microorganisms5 used for food and feed production. Care and Use of Laboratory Animals on performance goals as opposed to engineering approaches is a theme that resonates throughout. Coronavirus: Find the latest articles and preprints ... Get a printable copy (PDF file) of the complete article (149K), or click on a page image below to browse page by page. The most important item on a rodent breeding bin is the cage ID/breeding record card. Backcross. endstream endobj startxref 3694 0 obj <>stream MEENAKSHI M.Sc. To comply with the Animal Welfare Ordinance and avoid mishandling of animals in research. Inbreeding: When breeding is between animals of the same breed for 4-6 genera­tions, it is called inbreeding. Genetic evaluation of individual animals in a breeding population, selection of the best individuals for traits of importance in some sense (adaptation, production, economic), followed by mating of selected individuals to generate the next generation of animals. The goal of that course was to train students to program new ideas in animal breeding. Use of Laboratory Animals in Biomedical and Behavioral Research (1988) Animals for Research: A Directory of Sources, Tenth Edition and Supplement (1979) Amphibians: Guidelines for the Breeding, Care and Management of Laboratory Animals (1974) Copies of these reports may be ordered from the National Academies Press (800) 624-6242 or (202) 334-3313 An additional point of concern are the reproduction techniques used in conventional breeding. The Jackson Laboratory Handbook on Genetically Standardized Mice . This handbook attempts to provide a basic guide to anaesthesia for research workers and animal technicians. This card records the breeding of 1-2 female rodents per cage. Basic types of establishments for animal keeping are breeding / supply establishments and user establishments. In natural mating a breeding male is actually used for mating with the females. Federal Regulations and The Guide for the Care and Use of Laboratory Animals require appropriate management and housing for breeding. . CPCSEA Guidelines for Laboratory Animal Facility - 2015 61 -96 8. Biotechnology encompasses a number of tools and elements of conventional breeding techniques, An additional point of concern are the reproduction techniques used in conventional breeding. The other method is artificial insemination. Laboratory quality standards and their implementation  World Health Organization. A. females in a week. • The book covers the discipline of animal breeding from its history, quantitative genetic principles, selection, mating systems and the breeding methods … Felt, ... Hussein I. Hussein, in The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents, 2012. Reilly and M.A. I routinely witnessed ... for the Care and Use of Laboratory Animals, published in 2011, embraces this view (albeit without the regulatory force of the Animal Welfare Act). Regional Office for the Western Pacific (‎ Manila : WHO Regional Office for the Western Pacific , 2011 )‎ establish a laboratory animal health monitoring (HM) programme as an integrated part of any quality assur-ance system. Selecting for breeding animals with superior EBV in growth rate, egg, meat, milk, or wool production, or with other desirable traits has revolutionized livestock production throughout the … Other new reports, such as the 1997 Occupational Health and Safety in the Care and Use of Research Animals and the 1998 The Psychological Well-Being of �|ÚŸT³MÙ ³cä$60qzòş�j¦#§â�¾2B©’�Ÿ6�e~¤à'×wÀ¬ù‡Ğ–ì0œO‘¦î�ó¨è :†&�¤š8��M>x �N:?ôÑæ°ÏT¤×éP=‚bÙ%M%ß …Ú“. The programme provides sound training in these basic subjects that. The number of animals can only be approximated in advance because it is impossible to predict the exact number and sex of offspring. The primary enclosure provides the limits of the animal’s immediate environment. Recognition and Alleviation of Pain in Laboratory Animals (2009) Scientific and Humane Issues in the Use of Random Source Dogs and Cats for Research (2009) Recognition and Alleviation of Distress in Laboratory Animals (2008) Toxicity Testing in the 21st Century: A Vision and a Strategy (2007) appropriate breeding schemes, weaning ages, and methods for identification of individual animals. … II. Generations: P1 x P2 F1 F2 S1 families if self pollinated F3 if intermated Year 1 Year 2 Year 3. Vertebrate Animals Used in Testing, Research, and Training. . INSTITUTE FOR LAbORATORy ANIMAL RESEARCH PUbLICATIONS. In 1985, Congress enacted three laws that dealt with labora- ... Charles River Breeding Laboratories, Inc. Wilmington, MA Earle W. Brauer Revlon Research Center, Inc. ... of alternative methods to animal research, experi-mentation, and testing” from the Chairman of … Breeding of and Experiments on Animals (Control and Supervision) Rules, 2001 42 -44 5. The report concludes that: Key technologies relating to animal breeding have a long history and breakthroughs typically involve new methods or technologies rather than depending on genetic material per se; 2. Methods of Mating Livestock: The two method of mating livestock breeding is natural and artificial. The macroenvironment is the physical environment of the secondary enclosure (suc h as an animal holding room, a barn, etc.). Similarly, the Institute of To comply with the Animal Welfare Ordinance and avoid mishandling of animals in research. breeding animals), dogs, and other social species were individually housed. The reproductive system of the fowl, however, differs in form and function from the other domestic animals covered in this lesson. of the penis. Methods of Animal Breeding: Two methods of animals breeding are: inbreeding and out breeding, based mainly on breeding work with cattle. Animals (Scientific Procedures) Act, 1986 and associated guidelines, EU Directive 2010/63/EU for animal experiments, or the National Institutes of Health guide for the care and use of Laboratory animals (NIH Publications No. Animals (Scientific Procedures) Act, 1986 and associated guidelines, EU Directive 2010/63/EU for animal experiments, or the National Institutes of Health guide for the care and use of Laboratory animals (NIH Publications No. Inbreeding may be explained by taking an example of cows and bulls. Rose 6 1.1 Introduction 6 1.2 Minimisation of pain, distress, fear and anxiety 6 1.3 Methods of euthanasia 9 1.4 Special considerations with the age of the animal 12 1.5 Signs of death 14 1.6 Disposal of carcases 15 1. Large numbers of animals may be required to maintain a breeding colony. Hundreds of animals may be 'created' in an attempt to obtain a transgenic individual with a particular desired set of traits. Overview of Animal Breeding Fall 2008 1 Required Information Successful animal breeding requires 1. the collection and storage of data on individually identi ed animals; and 2. complete pedigree information about the sire and dam of each animal. Furthermore, processes Mouse stocks and breeding methods were as de-scribed by Bruce & Emmens (1948). 345 . But these techniques are 'artificial' and they deprive animals of natural mating behaviour and negatively affect the animals' welfare and integrity. Breeding of and Experiments on Animals (Control and Supervision) Rules, 2006 45 -48 6. Several sections of the guidelines have yet to be finalised, but the Councils are now issuing those relating to housing and care of laboratory animals. 1st Year ANIMAL HANDLING TECHNIQUES 2. B. are essential to animal breeding and lead to the acquisition of. Breeding is sexual reproduction that produces offspring, usually animals or plants. One is to obtain licence from the Home Department for using them on experimental purposes. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities—a resource of proven value, now updated and expanded. domestic animals (2). Laboratory animals in most countries are protected by the Law “Cruelty to Animals Act”. 3 The various techniques for altering the genetic make-up of an animal are explained in the report. Mouse stocks and breeding methods were as de-scribed by Bruce & Emmens (1948). Laboratory Animals, 2002), with the intention of harmonizing HM pro-grammes. The only advantage of following a commercial crop on station is that a commercial crop is establish a laboratory animal health monitoring (HM) programme as an integrated part of any quality assur-ance system. Animal Breeding and Reproduction Biotechnology Finally, reproduction biotechnology, that. accordance with the U.K. The macroenvironment is the physical environment of the secondary enclosure (suc h as an animal holding room, a barn, etc.). Breeding Strategies for Maintaining Colonies of Laboratory Mice A Jackson Laboratory Resource Manual This manual describes breeding strategies and techniques for maintaining colonies of laboratory mice. Thi s comparison was made first over a 10-week period but the animals were maintained in 1st Year ANIMAL HANDLING TECHNIQUES 2. A NOTE ON THE BREEDING OF GUINEA-PIGS WITHOUT FRESH GREEN FOOD BY H. M. BRUCE From the National Institute for Medical Research, London, N.W. use of laboratory animals. Feeding and breeding of laboratory animals III. Laboratory Animals, 2002), with the intention of harmonizing HM pro-grammes. Random breeding methods are used to maintain outbred stock. Reproduction and Breeding Techniques for Laboratory Animals. Rats respond to considerate and skilful handling and time and effort spent here will pay dividends during the course of the experiment in the form of more relaxed animals and in some cases better and more reproducible experimental results. It rotates and sprays semen during mating. used by all persons responsible for laboratory animals and particularly by licensees and others now working under the authority of the Animals (Scientific Procedures) Act, 1986. Methods of Mating Livestock: The two method of mating livestock breeding is natural and artificial. These techniques have been developed and used by The Jackson Laboratory for nearly 80 years. Breeding Strategies for Maintaining Colonies of Laboratory Mice A Jackson Laboratory Resource Manual Th is manual describes breeding strategies and techniques for maintaining colonies of laboratory mice. Reilly and M.A. accordance with the U.K. This handbook attempts to provide a basic guide to anaesthesia for research workers and animal technicians. OBJECTIVES To provide basic concept of animal handling to new user. Testicles – As in the other animals, sperm and hormones are produced in the testicles. animals must take account of wider issues than the science alone, but the Society wishes to stress the importance of informing such debate with sound scientific evidence. Artificial insemination (AI) and embryo transfer (ET) are commonplace in conventional animal breeding. Thi s comparison was made first over a 10-week period but the animals were maintained in 3682 0 obj <>/Filter/FlateDecode/ID[<32FBC5F92B59443492AA5618E7523721><38EEA92E5768D94AA9E883AA2B98B893>]/Index[3658 37]/Info 3657 0 R/Length 116/Prev 1492729/Root 3659 0 R/Size 3695/Type/XRef/W[1 3 1]>>stream Several sections of the guidelines have yet to be finalised, but the Councils are now issuing those relating to housing and care of laboratory animals. Section 1 Animal Welfare Considerations J.S. Breeding System. Inbreeding has not been initiated; instead, systematic mating of cousins is used in an attempt to preserve heterozygosity, since this is thought to be better than random mating in smaller … %PDF-1.6 %���� females in a week. I n a first experi-ment, diet 39 was compared with diet 32, the highly effective breeding diet described in the above paper (see Table 1). Basic types of establishments for animal keeping are breeding / supply establishments and user establishments. e���n�On�nҌ.i�EEܱ���]���wg/_��4�Nٍ� ����O�xGmR������Itk>c. Breeding may specifically refer to: Breeding in the wild, the natural process of reproduction in the animal kingdom Animal husbandry, through selected specimens such as mices ,rats dogs, horses, and rabbits 5Department of Pharmacology Total number of HTML views: 0. Programming was in Fortran because Fortran programs are relatively easy for numerical problems, and many existing packages in animal breeding still useful at that time were written in Fortran. These include genetics, statistics, reproductive physiology, computer science, and molecular genetics. used by all persons responsible for laboratory animals and particularly by licensees and others now working under the authority of the Animals (Scientific Procedures) Act, 1986. ... Full text views reflects PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views. Some of these animals may suffer severe, even lethal unexpected effects, such as the development of tumours, brain defects, limb Some, such as selective breeding or exposure to System of breeding. %%EOF An example is the crossbreeding of Yorkshire and Duroc breeds of pigs. Get a printable copy (PDF file) of the complete article (149K), or click on a page image below to browse page by page. 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